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Senescent Cell Removal Extends Lifespan of Mice by 35%



 

 

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This is an excerpt from my upcoming revised edition of Anti Aging Nutrition Secrets. The Fountain of Youth Seekers Guide to Longevity


Senescent Cell Removal is the term used to remove “senescent” (worn-out, cells that accumulate with age). When researchers genetically modified mice to have genes that specifically targeted and destroyed senescent cells, the mice lived 25 to 35 per cent longer in good health. They also remained more active with healthy hearts and kidneys.  Their body tissues and organs also showed less evidence of damaging inflammation.

 

The Destructive Effects of Senescent Cells

 

Due to their age, Senescent Cells no longer divide, but instead secrete molecules that do destructive harm and damage to neighboring tissues and trigger inflammation. Our body's immune system naturally sweeps these cells away regularly, however as a person ages, the process becomes less effective with time. The treatment showed no negative side-effects.


Calorie Restriction


Another study published in March 2015 titled: Serum from calorie-restricted animals delays senescence and extends the lifespan of normal human fibroblasts in vitro, conducted by Rafael de Cabo, and colleagues found that calorie-restricted animals had a significantly extended lifespan due to delayed senescence.



Excessive Iron


Another study published in October 2003 titled: Iron Accumulation During Cellular Senescence in Human Fibroblasts In Vitro and conducted by David Killilea and colleagues found that as a person got older, they accumulated increased levels of iron in their body, thus accelerating the rate of cellular senescence.


Chitosan 


Another study published in October 2015 titled: Chitosan Treatment Delays the Induction of Senescence in Human Foreskin Fibroblast Strains and conducted by Ching-Wen Tsai and colleagues found that Chitosan delayed cellular senescence.


Vitamin E


Another study published in November 2015 titled: Vitamin E Supplementation Delays Cellular Senescence In Vitro and conducted by Giorgio La Fata found that Vitamin E delayed cellular senescence. 

 

Does Ginseng help Sweep Senescent Cells from the body?

 

In a study published in June 2009 titled: Mechanisms of delay endothelial cell replicative senescence by extracts from Panax ginseng, Panax notoginseng and Ligusticum chuanxiong, and conducted by J. Yang and colleagues, the study concluded that extracts of P. ginseng, P. notoginseng and L. chuanxiong delayed endothelial cell replicative senescence and that extracts of the herbs could decrease the production and delay in vitro senescence.


Summary


While none of these compounds were able to specifically target and destroy senescent cells, by taking the above extracts it can greatly delay the onset of Cellular Senescence.


 





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